Focuses on the role of non-coding RNA in crop antiviral defense and the function of organelle interaction in organism resistance response; Analyzes the interaction among pathogen, host and insect vector at the aspects of molecular biology, cell biology and omics; Explores the dynamic balance of membraneless organelle that contributes to RNA silencing and crop-virus interaction, and the role of membraneless organelles in the regulation of virus replication and host anti-viral resistance; Investigates the regulatory function of lncRNA in crop disease resistance, and explores the regulatory network of non-coding RNA in crops. Explores the roles of non-coding RNAs in mammalian cell immunity and the underlying mechanisms.