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Dr. Wei GUO
Secretary Dan YU
Dr. Yun-Dan WANG
Dr. Xiao-Jiao GUO
Dr. He Jing
Dr. Ding Ding

Dr. Feng CUI
Dr. Wan ZHAO
Dr. Chen Bing
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  Dr. Wei GUO

Dr. Wei GUO

+86-10-64806029  /
The State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
Group of Eco-genomics and Adaptation
1999-2003 Bachelor of Science, Reproductive Biology, College of Life Science, Inner Mongolia University (IMU)
2003-2010 Ph.D. Molecular Ecology, Institute of Zoology (IOZ), Chinese Academy of Sciences (CAS)
2010-2012 Assistant Professor , IOZ,CAS
2013-now Associate Professor, IOZ.CAS

Research Interests:
Molecular Mechanisms of Insect Epigenetics and Hormone Regulation.

Awards and Honors:
2011 Johnson & Johnson Asia Outstanding Graduate Thesis Award in Bio-tech.

Selected Publications:
  1. Ren D*, Guo W*, Yang P*, Song J, He J, Zhao L, Kang L: Structural and functional differentiation of a fat body-like tissue adhering to testis follicles facilitates spermatogenesis in locusts. Insect Biochemistry and Molecular Biology 2019, 113:103207.
  2. Guo W*, Wu Z*, Yang L, Cai Z, Zhao L, Zhou S: Juvenile hormone-dependent Kazal-type serine protease inhibitor Greglin safeguards insect vitellogenesis and egg production. FASEB Journal 2019, 33:917-927.
  3. Wu Z*, Guo W*, Yang L, He Q, Zhou S: Juvenile hormone promotes locust fat body cell polyploidization and vitellogenesis by activating the transcription of Cdk6 and E2f1. Insect Biochemistry and Molecular Biology 2018, 102:1-10.
  4. Guo W, Ren D, Zhao L, Jiang F, Song J, Wang X, Kang L: Identification of odorant-binding proteins (OBPs) and functional analysis of phase-related OBPs in the migratory locust. Frontiers in physiology 2018, 9:984.
  5. Luo M, Li D, Wang Z, Guo W, Kang L, Zhou S: Juvenile hormone differentially regulates two Grp78 genes encoding protein chaperones required for insect fat body cell homeostasis and vitellogenesis. Journal of Biological Chemistry 2017, 292:8823-8834.
  6. Wu Z, Guo W, Xie Y, Zhou S: Juvenile hormone activates the transcription of cell-division-cycle 6 (cdc6) for polyploidy-dependent insect vitellogenesis and oogenesis. Journal of Biological Chemistry 2016, 291:5418-5427.
  7. Wang XH, Fang XD, Yang PC, Jiang XT, Jiang F, Zhao DJ, Li BL, Cui F, Wei JN, Ma CA…Guo W et al: The locust genome provides insight into swarm formation and long-distance flight. Nature communications 2014, 5:1-9.
  8. Liu L, Zheng H, Jiang F, Guo W, Zhou S: Comparative transcriptional analysis of asexual and sexual morphs reveals possible mechanisms in reproductive polyphenism of the cotton aphid. PLoS One 2014, 9(6):e99506.
  9. Guo W*, Wu Z*, Song J, Jiang F, Wang Z, Deng S, W. VK, Zhou S: Juvenile hormone-receptor complex acts on mcm4 and mcm7 to promote polyploidy and vitellogenesis in the migratory locust. PLoS Genetics 2014, 10:e1004702.
  10. Song S, Jiang F, Yuan J, Guo W, Miao Y: Exceptionally high cumulative percentage of NUMTs originating from linear mitochondrial DNA molecules in the Hydra magnipapillata genome. BMC genomics 2013, 14:447.
  11. Song J, Guo W, Jiang F, Kang L, Zhou S: Argonaute 1 is indispensable for juvenile hormone mediated oogenesis in the migratory locust, Locusta migratoria. Insect Biochemistry and Molecular Biology 2013, 43:879-887.
  12. Wang H, Ma Z, Cui F, Wang X, Guo W, Lin Z, Yang P, Kang L: Parental phase status affects the cold hardiness of progeny eggs in locusts. Functional Ecology 2012, 26:379-389.
  13. Jiang F, Yang M, Guo W, Wang X, Kang L: Large-scale transcriptome analysis of retroelements in the migratory locust, Locusta migratoria. PLoS One 2012, 7:e40532.
  14. Ma Z, Guo W, Guo X, Wang X, Kang L: Modulation of behavioral phase changes of the migratory locust by the catecholamine metabolic pathway. Proceedings of the National Academy of Sciences of the United States of America 2011, 108:3882-3887.
  15. Guo W*, Wang X*, Ma Z, Xue L, Han J, Yu D, Kang L: CSP and takeout genes modulate the switch between attraction and repulsion during behavioral phase change in the migratory locust. PLoS Genetics 2011, 7:e1001291.
  16. Guo W*, Wang X*, Zhao D, Yang P, Kang L: Molecular cloning and temporal-spatial expression of I element in gregarious and solitary locusts. Journal of Insect Physiology 2010, 56:943-948.
  17. Wang H, Wang X, Zhou C, Huang L, Zhang S, Guo W, Kang L: cDNA cloning of heat shock proteins and their expression in the two phases of the migratory locust. Insect Molecular Biology 2007, 16:207-219.
  18. Wang H, Zhou C, Guo W, Kang L: Thermoperiodic acclimations enhance cold hardiness of the eggs of the migratory locust. Cryobiology 2006, 53:206-217

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Address: 1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China